2011-12 General Catalog

Physical and Biological Sciences Undergraduate Affairs Office
387 Thimann Laboratories
(831) 459-4143
http://undergrad.pbsci.ucsc.edu

Program Description | Faculty
Ecology and Evolutionary Course Decriptions | Molecular, Cell, and Developmental Course Descriptions

Biology: Ecology and Evolutionary

Lower-Division Courses

20B. Development and Physiology. F,W,S
Topics in morphology, physiology, development, genetics, and endocrinology selected to exemplify current issues and perspectives in organismic biology. Prerequisite(s): BIOL 20A. I. Parker, R. Mehta, J. Pittermann, T. Williams

20C. Ecology and Evolution. F,W,S
Introduction to ecology and evolution covering principles of evolution at the molecular, organismal, and population levels. Evolutionary topics include genetic and phenotypic variation, natural selection, adaptation, speciation, and macroevolution. Also covers behavioral, population, and community ecology including applied ecological issues. . B. Marinovic

75. Scientific Diving Certification (2 credits). F,S
Prerequisite for course 161/L, Kelp Forest Ecology, and all research diving performed under the auspices of UCSC or other academic institutions. Course work includes lectures and scuba diving. Topics include subtidal sampling techniques, navigation, low visibility diving, search and recovery, rescues, small boat use, oxygen administration for divers, technical blue water deep diving, physics, and physiology. Apply online at http://www2.ucsc.edu/sci-diving. Students are billed a course materials fee that covers costs for equipment use, materials, and transportation. Prerequisite(s): skill level equal to Advanced Scuba Diver Certification, pass scuba physical, provide own scuba gear, be certified in CPR and First Aid; and interview: pass swim test and scuba skills test. Enrollment limited to 16. The Staff

80N. Biology of Human Health and Nutrition. W,S
An introduction to the biology of human nutrition and its effects on human health. The course explores how nutrient balance, exercise, and age interact in their effects on human health, fitness, and disease. (General Education Code(s): SI, T-2 Natural Sciences.) J. Thompson

80P. Infectious Diseases and Human Populations. W,S
An overview of the biology of infectious diseases in human societies including why diseases vary in severity, how human bodies defend themselves, and how public health efforts cope with the problem of rapidly evolving pathogens. (General Education Code(s): SI, T-2 Natural Sciences.) J. Thompson

99. Tutorial. F,W,S
Individual, directed study for undergraduates. Students submit petition to sponsoring agency. May be repeated for credit. The Staff

Upper-Division Courses

107. Ecology. W,S
Focuses on physiological, behavioral, and population ecology, and on linking ecological processes to evolution. It includes basic principles, experimental approaches, concepts of modeling, and applications to ecological problems. Prerequisite(s):satisfaction of the Entry Level Writing and Composition requirements; BIOL 20A, BIOE 20B, and BIOE 20C. (W) B. Lyon, (S) J. Estes

108. Marine Ecology. W
Paradigms and designs in marine ecology. A review of the paradigms that have shaped our understanding of marine ecology; analysis and discussion of experiments with these paradigms. Students cannot receive credit for this course and course 208. Prerequisite(s): satisfaction of the Entry Level Writing and Composition requirements; BIOL 20A, BIOE 20B, and BIOE 20C; BIOE 107 or 140 recommended. Enrollment restricted to juniors and seniors. M. Carr, P. Raimondi

109. Evolution. F,W
An examination of the history and mechanisms of evolutionary change. Topics include molecular evolution, natural and sexual selection, adaptation, speciation, biogeography, and macroevolution. Prerequisite(s): satisfaction of the Entry Level Writing and Composition requirements; BIOL 20A, BIOE 20B, BIOE 20C, and BIOL 105. G. Bernardi, (F) G. Pogson

112. Ornithology. F
Introduction to the evolution, ecology, behavior, and natural history of birds, using exemplary case histories to illustrate key concepts in evolution, ecology, and behavior. Prerequisite(s): BIOE 107, BIOE 109, or BIOE 140. Concurrent enrollment in BIOE 112L is required. B. Lyon

112L. Ornithology Field Studies (2 credits). F
Field trips introduce students to field identification skills and field investigation of census, foraging behavior, migration, social behavior, and communication. Examination of specimens in the laboratory will be used to highlight the diversity and taxonomy of birds. Students are billed a materials fee. Some field trips may require students to provide their own transportation. Prerequisite(s): BIOE 107, BIOE 109, or BIOE 140. Concurrent enrollment in BIOE 112 is required. Offered in alternate academic years. B. Lyon

114. Herpetology. S
Lectures introduce students to evolution, development, physiology, behavior, ecology, and life history of reptiles and amphibians. The materials integrate with conceptual and theoretical issues of ecology, evolution, physiology, and behavior. Prerequisite(s): BIOE 107, BIOE 109, BIOE 110, or BIOE 140. Concurrent enrollment in BIOE 114L required. Offered in alternate academic years. B. Sinervo

114L. Field Methods in Herpetological Research (2 credits). S
Field trips introduce students to natural history, censusing techniques, physiological ecology, and behavioral analysis of reptiles and amphibians. Laboratories introduce students to techniques for analyzing behavior and physiology. Field studies culminate with a group project in a natural setting. Some field trips may be held on weekends due to weather considerations. Some field trips may require students to provide their own transportation, some transportation will be provided by UCSC. Students are billed a materials fee. Prerequisite(s): BIOE 107, 109, 110, or 140. Concurrent enrollment in BIOE 114 is required. Offered in alternate academic years. B. Sinervo

117. Systematic Botany of Flowering Plants. S
An examination of the taxonomy and evolution of flowering plants. Special topics include phylogenetics and cladistics, plant species concepts, and modern methods of systematic research. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C. Must be taken concurrently with BIOE 117L. K. Kay

117L. Systematic Botany of Flowering Plants Laboratory (2 credits). S
Weekly laboratory concerned primarily with California flora and plant families. Several field trips. Students are billed a materials fee. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C. Must be taken concurrently with BIOE 117. K. Kay

120. Marine Botany. S
An introduction to the biology of marine algae, fungi, and angiosperms with regard to form and function. Major boreal, temperate, and tropical marine plant communities. Lecture format. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C. Must be taken concurrently with BIOE 120L. The Staff

120L. Marine Botany Laboratory (2 credits). S
One laboratory weekly and several field trips. Focuses on marine algae, fungi, and angiosperms. Students are billed a materials fee. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C. Must be taken concurrently with BIOE 120. The Staff

122. Invertebrate Zoology. W
An examination of invertebrates and their habitats. Lecture format. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C. BIOE 122L must be taken concurrently. B. Marinovic

122L. Invertebrate Zoology Laboratory (2 credits). W
An examination of invertebrates and their habitats. Weekly laboratories or field trips. Students are billed a materials fee. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C. BIOE 122 must be taken concurrently. B. Marinovic

127. Ichthyology. F
An introduction to the biology of jawless, cartilaginous, and bony fishes—their classification, evolution, form, physiology, and ecology. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C. BIOE 127L must be taken concurrently. Offered in alternate academic years. G. Bernardi

127L. Ichthyology Laboratory (2 credits). F
One laboratory session a week and several field trips to study the biology of fish. Students are billed a materials fee. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C. BIOE 127 must be taken concurrently. Offered in alternate academic years. G. Bernardi

129. Biology of Marine Mammals. S
A survey of cetaceans, pinnipeds, sirenians, and sea otters, including natural history, systematics, physiology, behavior, anatomy, and conservation. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C; BIOL 110 is recommended. D. Costa

129L. Biology of Marine Mammals Laboratory (2 credits). S
Covers the basics of marine mammal taxonomy, anatomy, and field methods with an emphasis on local field identification and understanding of local species. Will include field trips to Long Marine Lab, Ano Nuevo, and Monterey Bay. Students are billed a materials fee. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C. Must be taken concurrently with BIOE 129. D. Costa

131. Animal Physiology. S
Principles and concepts underlying the function of tissues and organ systems in animals with emphasis on vertebrate systems. Students cannot receive credit for this course and BIOL 130. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C. T. Williams

131L. Animal Physiology Laboratory (2 credits). S
Experiments conducted with primary focus on quantitative physiological principles of organ systems and intact organisms. Students cannot receive credit for this course and course 130L. Students are billed a materials fee. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C. Concurrent enrollment in BIOE 131 is required. T. Williams

133. Exercise Physiology. W
An advanced-level course concerning physiological and biochemical processes associated with human performance. Emphasis is on the integration of organ systems for exercise. Topics include metabolism and fuel utilization, cardiovascular and respiratory dynamics during activity, and the effects of training. Requires a good understanding of basic physiological function and anatomy. Prerequisite(s): BIOL 20A, BIOE 20B and 20C. BIOE 131 recommended. Concurrent enrollment in BIOE 133L required. T. Williams

133L. Exercise Physiology Laboratory (2 credits). W
An introduction to basic measurement techniques used in assessing the physiological response of humans to exercise. Sessions cover oxygen consumption, respiratory rate, and heart rate monitoring during aerobic and anaerobic activity. Prerequisite(s): BIOL 20A, and BIOE 20B and 20C. BIOE 131 recommended. Concurrent enrollment in BIOE 133 is required. T. Williams

135. Plant Physiology. W
Cellular and organismal functions important in the life of green plants. Prerequisite(s): BIOL 20A and BIOE 20B and 20C; concurrent enrollment in course 135L is required. J. Pittermann

135L. Plant Physiology Laboratory (2 credits). W
Weekly laboratory concerning the cellular and organismal functions of green plants. Students are billed a materials fee. Prerequisite(s): BIOL 20A and BIOE 20B and BIOE 20C; concurrent enrollment in course 135. J. Pittermann

140. Behavioral Ecology. F
An introduction to social and reproductive behavior. Emphasis on studies of vertebrates in their natural habitat. Ideas concerning the evolution of social behavior, mating systems, and individual reproductive strategies. Case histories of well-studied animals that illustrate key principles in courtship and mating, parental behavior, and food-getting behavior. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C. The Staff

141L. Behavioral Ecology Field Course. *
A field-based course introducing students to concepts and methods for studying behavioral ecology in nature. Students will conduct observations and field experiments on various local model organisms including elephant seals, hummingbirds, sparrows, lizards, ants, bees, frogs, and salamanders. Students are billed a materials fee. Prerequisite(s): BIOE 107 or BIOE 140 or BIOE 110; satisfaction of the Entry Level Writing and Composition requirements. Enrollment limited to 25. Offered in alternate academic years. (General Education Code(s): W.) B. Sinervo, B. Lyon

145. Plant Ecology. F
An exploration of the ecology of plant form, function, distribution, abundance, and diversity. Topics include plant adaptations to environmental conditions, life history variation, competition, reproductive ecology, herbivory, and patterns of diversity. Lecture with discussions of original papers and independent field project. Students cannot receive credit for this course and course 245. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C. BIOE 107 is recommended. I. Parker

145L. Field Methods in Plant Ecology. F
Hands-on exploration of the concepts and techniques of plant ecology. A combination of lab, greenhouse, and field-based exercises (irrespective of weather conditions). Statistical analysis and scientific writing. One required weekend field trip. Students cannot receive credit for this course and course 245L. Students are billed a materials fee. Prerequisite(s): satisfaction of the Entry Level Writing and Composition requirements; BIOL 20A, BIOE 20B, and BIOE 20C. Concurrent enrollment in BIOE 145 is required. BIOE 107 is recommended. (General Education Code(s): W.) I. Parker

147. Community Ecology. S
Develops the major themes of community biology: structure, trophic dynamics, succession, complex interactions among species, herbivory, evolution and coevolution. Uses case histories of well-studied marine and terrestrial systems. Students cannot receive credit for this course and course 247. Prerequisite(s): BIOE 107, 108, 145, 155 or 159A; or Environmental Studies 24 by permission of instructor. L. Fox

148. Quantitative Ecology. S
Quantitative treatment of the central concepts and applications of theoretical ecology. Emphasis on the mathematical modeling of single populations and species interactions, and the integration of models with data. Topics include stochastic and deterministic processes of extinction; discrete- and continuous-time models of growth and population viability analysis relevant to small and harvested populations; numeric and analytical investigations of dynamics and stability; introduction to model-fitting in information theoretic framework using R and/or MATLAB. Prerequisite(s): BIOE 107. M. Tinker

149. Disease Ecology. W
Focuses on the ecological and evolutionary processes that drive the transmission of pathogens between hosts; the impact of disease on host populations; and what causes the emergence of an infectious disease. Includes theoretical framework, description of field techniques, and discussion of wildlife and human diseases including malaria, West Nile virus, Lyme disease, HIV, avian influenza (bird flu), Chikungunya, tuberculosis, chytridiomycosis, and Ebola. Prerequisite(s): BIOL 20A, and BIOE 20B and 20C and 107. A. Kilpatrick

150. Ecological Field Methods. *

Lectures and laboratory computer exercises designed to familiarize students with research methods, study design, statistical approaches, and analysis tools for ecological research. Students cannot receive credit for this course and Environmental Studies 104A. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C; concurrent enrollment in BIOE 150L is required. BIOE 107, 108, 140, or 147 recommended. Enrollment limited to 25. D. Croll

150L. Ecological Field Methods Laboratory. *

Field-oriented course in the study of animal ecology and behavior. Combines overview of methodologies and approaches to field research with practical field studies. Students are billed a materials fee. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C; concurrent enrollment in BIOE 150 is required. BIOE 107, 108, 140, or 147 recommended. Enrollment limited to 25. (General Education Code(s): W.) D. Croll

151A. Ecology and Conservation in Practice Supercourse: Ecological Field Methods. S
An intensive, on-site learning experience in terrestrial field ecology and conservation, using the University of California Natural Reserves. Students study advance concepts in ecology, conservation, and field methods for four weeks, then experience total immersion in field research at the UC Natural Reserves. Lectures, field experiments, and computer exercises familiarize students with research methods, study design, statistical approaches, and analytical tools for ecological research. Enrollment by application. Prerequisite(s): BIOL 20A, BIOE 20B, BIOE 20C or ENVS 23, 24, 100; and AMS 7 and 7L. Concurrent enrollment in BIOE 151B-C-D or ENVS 109B-C-D is required. Satisfies the senior exit requirement for biological sciences majors and satisfies the senior exit requirement for environmental studies majors by prior approval. Students cannot receive credit for this course and BIOE 107, 107L, ENVS 104A or 196A. (Also offered as Environmental Studies 109A. Students cannot receive credit for both courses.) D. Croll, E. Zavaleta

151B. Ecology and Conservation in Practice Supercourse: Ecological Field Methods Laboratory. S
Field-oriented course in ecological research. Combines overview of methodologies and approaches to field research with practical field studies. Students complete field projects in ecology and also learn the natural history of the flora and fauna of California. Students are billed a materials fee. Enrollment by application. Prerequisite(s): Entry Level Writing and Composition requirements; BIOL 20A, BIOE 20B, BIOE 20C or ENVS 23, 24, 100; and AMS 7 and 7L. Concurrent enrollment in BIOE 151A-C-D or ENVS 109A-C-D is required. Satisfies the senior exit requirement for biological sciences majors and satisfies the senior exit requirement for environmental studies majors by prior approval. Students cannot receive credit for this course and BIOE 150, 150L, ENVS 104A or 196A. (Also offered as Environmental Studies 109B. Students cannot receive credit for both courses.) (General Education Code(s): W.) D. Croll, E. Zavaleta

151C. Ecology and Conservation in Practice Supercourse: Functions and Processes of Terrestrial Ecosystems. S
From lectures and discussion of terrestrial community and ecosystem ecology, students work individually or in small groups to present an idea for a project, review relevant literature, develop a research question/hypothesis, design and perform an experiment, collect and analyze data, and write a report. The instructor evaluates the feasibility of each student's project before it begins. Enrollment by application. Prerequisite(s): BIOL 20A, BIOE 20B, BIOE 20C or ENVS 23, 24, 100; and AMS 7 and 7L. Concurrent enrollment in BIOE 151A-B-D or ENVS 109A-B-D is required. Satisfies the senior exit requirement for biological sciences majors and satisfies the senior exit requirement for environmental studies majors by prior approval. Students cannot receive credit for this course and BIOE 150, 150L, ENVS 104A or 196A. (Also offered as Environmental Studies 109C. Students cannot receive credit for both courses.) D. Croll, E. Zavaleta

151D. Ecology and Conservation in Practice Supercourse: Conservation in Practice. S
Focuses on current issues in environmental and conservation biology and the emerging field methods used to address them. From field-oriented lectures about current issues in environmental and conservation biology, students pursue research project as individuals and small groups to develop hands-on experience with field skills in conservation research and resource management. Enrollment by application. Prerequisite(s): BIOL 20A, BIOE 20B, BIOE 20C or ENVS 23, 24, 100; and AMS 7 and 7L. Concurrent enrollment in BIOE 151A-B-C or ENVS 109A-B-C is required. Satisfies the senior exit requirement for biological sciences majors and satisfies the senior exit requirement for environmental studies majors by prior approval. Students cannot receive credit for this course and BIOE 150, 150L, ENVS 104A or 196A. (Also offered as Environmental Studies 109D. Students cannot receive credit for both courses.) D. Croll, E. Zavaleta

155. Freshwater Ecology. F
Provides an overview of the physical, chemical, and biological processes that characterize inland waters such as lakes, streams, rivers, and wetlands. Also addresses relationships between humans and freshwater, and discusses these challenges in conservation. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C. The Staff

158L. Marine Ecology Laboratory. S
Supervised individual research projects in experimental marine biology. Students carry out a complete research project, including (1) the formation of hypotheses; (2) the design and implementation of experiments; (3) collection, analysis, and interpretation of data; and (4) write-up of an oral presentation. Students are billed a materials fee. Prerequisite(s): BIOE 108; satisfaction of the Entry Level Writing and Composition requirements. Offered in alternate academic years. (General Education Code(s): W.) M. Carr, P. Raimondi

159A. Marine Ecology Field Quarter: Marine Ecology with Laboratory. *

Total immersion in marine ecology for very motivated students. Students develop a research project during first five weeks on campus and then spend five weeks of immersion in directed research without distraction in isolated locations off campus (past locations include the Gulf of California in Mexico and Moorea in French Polynesia). Not available through University Extension. No other courses may be taken during this quarter. Students must sign a contract agreeing to standards of behavior outlined in the UCSC Rule Book and by the instructors. Students are billed a materials, transportation (not airfare), and room and board fee. Paradigms and designs in marine ecology. A review of the paradigms that have shaped our understanding of marine ecology and analysis and discussion of experiments with these paradigms. Students carry out a complete research project, including the formation of hypotheses; the design and implementation of experiments; the collection, analysis, and interpretation of data; and the write-up and oral presentation of results. Admission by interview during previous winter quarter. BIOE 159A, 159B, 159C, and 159D are equivalent to BIOE 127, 127L, 108, and 158L for major requirements. Prerequisite(s): satisfaction of the Entry Level Writing and Composition requirements; BIOE 159A, 159B, 159C, and 159D must be taken concurrently. Enrollment limited to 26. Offered in alternate academic years. (General Education Code(s): W.) P. Raimondi

159B. Marine Ecology Field Quarter: Ichthyology with Laboratory. *

An introduction to the biology of jawless, cartilaginous, and bony fishes—their classification, evolution, form, physiology, and ecology. Admission by interview during previous winter quarter. BIOE 159A, 159B, 159C, and 159D are equivalent to BIOE 127, 127L, 108, and 158L for major requirements. BIOE 159A, 159B, 159C, and 159D must be taken concurrently. Enrollment limited to 26. Offered in alternate academic years. G. Bernardi

159C. Marine Ecology Field Quarter: Methods in Field Ecology. *

Students learn quantitative methods for field experiments and surveys. Emphasis will be on marine environments, but there will also be exposure to terrestrial systems. This is the lecture component to course 159D. No text is required for this course; instead, readings from the current literature will be assigned. Students are evaluated on written independent field project proposals and class participation. Admission by interview during previous winter quarter. BIOE 159A, 159B, 159C, and 159D are equivalent to BIOE 127, 127L, 108, and 158L for major requirements. BIOE 159A, 159B, 159C, and 159D must be taken concurrently. Enrollment limited to 26. Offered in alternate academic years. P. Raimondi

159D. Marine Ecology Field Quarter: Methods in Field Ecology Laboratory. *

This is laboratory portion of course 159C. Students carry out independent field projects under the supervision of course instructors. All work is done during the 5–6 week off-campus portion of course 159. Students are evaluated on field techniques, the final write-up of their independent field projects, and class participation. Admission by interview during previous winter quarter. BIOE 159A, 159B, 159C, and 159D are equivalent to BIOE 127, 127L, 108, and 158L for major requirements. BIOE 159A, 159B, 159C, and 159D must be taken concurrently. Enrollment limited to 26. Offered in alternate academic years. G. Bernardi

161. Kelp Forest Ecology. F,S
Study of organization of kelp forests as models for examining biological communities. The physical and biotic factors responsible for community organization of kelp forests are explored using original literature and data collected in BIOE 161L. Class meets one full morning each week. Prerequisite(s): by interview only; BIOL 20A, BIOE 20B, and BIOE 20C are required. Students must pass the University Research Diving Certification (contact the diving safety officer, Institute of Marine Sciences, for further information). Enrollment restricted to seniors. BIOE 161L must be taken concurrently; BIOE 107, 120/L, 122/L are recommended. Enrollment limited to 24. Offered in alternate academic years. M. Carr, P. Raimondi

161L. Kelp Forest Ecology Laboratory. F,S
Fieldwork using SCUBA to quantitatively and qualitatively examine the abundance and distribution of organisms in kelp forests, with additional laboratory work. Culminates with a directed individual research project. Class meets one full morning each week. Students are billed a materials fee. Admission by interview. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C; satisfaction of the Entry Level Writing and Composition requirements; BIOE 161 must be taken concurrently; BIOE 107, 120/L, 122/L are recommended. Students must pass the University Research Diving Certification (contact the Diving Safety Officer, Institute of Marine Sciences, for further information). Enrollment limited to 24. Offered in alternate academic years. (General Education Code(s): W.) M. Carr, P. Raimondi

163. Ecology of Reefs, Mangroves, and Seagrasses. W
Integrated treatment of coral reefs, sea grasses, and mangroves emphasizing interactions and processes through time. Major topics: biological and geological history, biogeography, evolution and ecology of dominant organisms, biodiversity, community and ecosystem ecology, geology, biogeochemistry, global change, human impacts. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C. D. Potts

165. Marine Conservation Biology. F
Initially undertakes an in-depth comparison of the biology and conservation of marine versus terrestrial ecosystems. With this foundation, course examines marine biodiversity loss resulting from overexploitation, habitat loss, species introduction, and pollution, with particular emphasis on the resulting trophic cascades, biodiversity losses, and climate change. Students cannot receive credit for this course and Environmental Studies 120. Prerequisite(s): BIOL 20A, BIOE 20B, and BIOE 20C; OCEA 101 recommended. D. Croll

172. Population Genetics. *

Basic population genetics and selected topics will be covered, including genetics of speciation, tempo and mode of evolution, genetics of social behavior, natural selection in human populations, and the impact of molecular studies on evolutionary theory. Students cannot receive credit for this course and BIOE 272. Prerequisite(s): BIOL 20A, BIOE 20B, BIOE 20C, and BIOL 105. Concurrent enrollment in BIOE 172L is required. Offered in alternate academic years. G. Pogson

172L. Population Genetics Laboratory (2 credits).

A companion course to 172, Population Genetics, that applies the theory developed in that course to related disciplines including conservation biology, ecology, agriculture, and population biology. Original scientific literature relating to the theory developed in BIOE 172 is read, and applied problem sets are solved by the students. Students cannot receive credit for this course and BIOE 272L. Prerequisite(s): BIOL 20A, BIOE 20B, BIOE 20C, and BIOL 105. Concurrent enrollment in BIOE 172 is required. Offered in alternate academic years. G. Pogson

183F. Undergraduate Research in Ecology and Evolutionary Biology (2 credits). F,W,S
Supervised undergraduate research on a project with an ecology and evolutionary biology faculty member for students considering a career based on biological research. Class reviews the philosophy of science, basic statistics, and library searches, and emphasizes how to input data, create graphs, and prepare results for publication, and talks. Enrollment restricted to junior and senior EEB majors conducting research project with EEB faculty member. The Staff

183L. Undergraduate Research in Ecology and Evolutionary Biology. F,W,S
Supervised undergraduate research on a project with an ecology and evolutionary biology faculty member for students considering a career based on biological research. Class reviews the philosophy of science, basic statistics, and library searches, and emphasizes how to input data, create graphs, and prepare results for publication, and talks. Prerequisite(s): satisfaction of the Entry Level Writing and Composition requirements; enrollment restricted to junior and senior EEB majors conducting research project with EEB faculty member. (General Education Code(s): W.) The Staff

188. Introduction to Science Writing. S
A rigorous examination and practice of the skills involved in writing articles about science, health, technology, and the environment for the general public. Covers the essential elements of news writing and explanatory journalism, including developing a story idea, interviewing scientists, fact checking, composition, and editing of multiple drafts about scientific research. (Also offered as Science Communication 160. Students cannot receive credit for both courses.) Prerequisite(s): satisfaction of the Entry Level Writing and C1, C2 requirements. Enrollment restricted to junior and senior biological sciences majors. Enrollment limited to 18. (General Education Code(s): W.) The Staff

190. Senior Seminar (2 credits). S
Satisfies the senior exit requirement for all biological sciences majors. (Also offered as Biology: Molecular Cell & Dev 190. Students cannot receive credit for both courses.) The Staff

195. Senior Thesis. F,W,S
An individually supervised course, with emphasis on independent research. Students required to submit a senior thesis. Enrollment restricted to majors in biology, ecology and evolution, marine biology, plant sciences, and the combined major with environmental studies. Students submit petition to sponsoring agency. The Staff

198. Independent Field Study. F,W,S
Provides for individual programs of study (a) by means other than the usual supervision in person, or (b) when the student is doing all or most of the course work off campus. With permission of the department, may be repeated for credit, or two or three courses taken concurrently. Students submit petition to sponsoring agency. May be repeated for credit. The Staff

198F. Independent Field Study (2 credits). F,W,S
Provides for two units of independent field study (a) by means other than the usual supervision in person, or (b) when the student is doing all or most of the course work off campus. Students submit petition to sponsoring agency. May be repeated for credit. The Staff

199. Tutorial. F,W,S
Reading, discussion, written reports, and laboratory research on selected biological topics, using facilities normally available on campus. Students submit petition to sponsoring agency. May be repeated for credit. The Staff

199F. Tutorial (2 credits). F,W,S
Two-unit Tutorial. Reading, discussion, written reports, and laboratory research on selected biological topics, using facilities normally available on campus. Students submit petition to sponsoring agency. May be repeated for credit. The Staff

Graduate Courses

200A. Scientific Skills. F
Exposes graduate students to teaching skills, understanding the scientific method, searching and organizing literature, grant proposal and scientific writing, data management and presentation, and scientific speaking. Students are evaluated on their participation and the quality of a written research proposal. Enrollment restricted to graduate students. M. Carr

200B. Advanced Organismal Biology. F
Consists of lectures focusing on pivotal topics in ecology and evolution. Relevant background material is developed followed by a critical analysis of readings from the primary literature. Designed to give graduate (and advanced undergraduate) students direct contact with the major areas of research that are currently at the forefront of organismal biology. Enrollment restricted to graduate students. L. Fox, A. Kilpatrick, D. Costa

208. Marine Ecology. W
Paradigms and designs in marine ecology. A review of the paradigms that have shaped our understanding of marine ecology; analysis and discussion of experiments with these paradigms. Students cannot receive credit for this course and course 108. Enrollment restricted to graduate students. M. Carr, P. Raimondi

245. Plant Ecology. F
An exploration of the ecology of plant form, function, distribution, abundance, and diversity. Topics include plant adaptations to environmental conditions, life history variation, competition, reproductive ecology, herbivory, and patterns of diversity. Lecture with discussions of original papers and independent field project. Students cannot receive credit for this course and course 145. Prerequisite(s): BIOE 107 or ENVS 24 or permission of instructor. Concurrent enrollment in BIOE 245L is required except by permission of instructor. Enrollment restricted to graduate students. I. Parker

245L. Field Methods in Plant Ecology Laboratory. F
Hands-on exploration of the concepts and techniques of plant ecology. A combination of lab, greenhouse, and field-based exercises (irrespective of weather conditions), statistical analysis, and scientific writing. One required weekend field trip. Students cannot receive credit for this course and course 145L. Concurrent enrollment in BIOE 245 is required. Enrollment restricted to graduate students. Enrollment limited to 2. I. Parker

247. Community Ecology. S
Develops the major themes of community ecology: structure, trophic dynamics, succession, complex interactions among species, herbivory, evolution, and coevolution. Uses case histories of well-studied marine and terrestrial systems. Students cannot receive credit for this course and course 147. Enrollment restricted to graduate students. L. Fox

258L. Experimental Marine Ecology. S
Supervised individual research projects in experimental marine biology. Students carry out a complete research project, including (1) the formation of hypotheses, (2) the design and implementation of experiments, (3) collection, analysis, and interpretation of data, and (4) the write-up of an oral presentation. Prerequisite(s): BIOE 208; and interview to assess ability to carry out field project. Enrollment limited to 20. Offered in alternate academic years. M. Carr, P. Raimondi

272. Population Genetics. *

Basic population genetics and selected topics are covered including genetics of speciation, tempo and mode of evolution, genetics of social behavior, natural selection in human populations, and the impact of molecular studies on evolutionary theory. Students cannot receive credit for this course and Biology 172. Concurrent enrollment in BIOE 272L is required. Enrollment restricted to graduate students. Offered in alternate academic years. G. Pogson

272L. Population Genetics Laboratory (2 credits).

A companion course to 272, Population Genetics, that applies the theory developed in that course to related disciplines including conservation biology, ecology, agriculture, and population biology. Original scientific literature relating to the theory developed in course 272 is read, and applied problem sets are solved by the students. Students cannot receive credit for this course and course 172L. Must be taken concurrently with BIOE 272. Enrollment restricted to graduate students. Offered in alternate academic years. G. Pogson

274. Evolutionary Game Theory. W
Reviews static equilibrium concepts, games of incomplete information, and the traditional theory of dynamic games in discrete time. Develops recent evolutionary game models, including replicator and best reply dynamics, and applications to economics, computer science, and biology. Prerequisite(s): upper-division math courses in probability theory are strongly recommended. Cannot receive credit for this course and Economics 166B or Computer Science 166B. (Also offered as Computer Science 272. Students cannot receive credit for both courses.) B. Sinervo, The Staff

279. Evolutionary Ecology. W
Analysis of the ways in which ongoing evolution and coevolution shape the ecological structure and dynamics of populations, species, and species interactions across geographic landscapes. Enrollment restricted to graduate students. J. Thompson

281A. Topics in Basic and Applied Marine Ecology. F,W,S
Seminar focusing on concepts in basic and applied ecology. Structure rotates quarterly between graduate student research and readings of journal articles and textbooks. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. Enrollment limited to 10. M. Carr

281B. Topics in Molecular Evolution (2 credits). F,W,S
A discussion of current research and literature review on the subject of molecular evolution. Primary focus on recent results on molecular phylogenetics and molecular population genetics. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. May be repeated for credit. G. Bernardi

281C. Topics in Physiological Ecology. F,W,S
An intensive seminar focusing on the interaction between physiological constraint and life history options and solutions employed by animals. Topics vary from comparative physiology to ecological theory. Participants are required to present results of their own research or review papers of interest. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. May be repeated for credit. D. Costa

281F. Ecological Research Topics. F,W,S
Intensive research and discussions on plant-animal interactions. All students undertake a research project and meet weekly with the faculty sponsor to monitor progress. The group meets weekly to discuss experimental design and analysis, specific problems related to the students' research, relevant research papers, or manuscripts that the group members are writing. Each student gives a formal presentation of research plans or progress each quarter. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. Enrollment limited to 10. May be repeated for credit. L. Fox

281H. Topics in Comparative Marine Physiology. F,W,S
Intensive seminar on selected topics in marine physiology. Students present results from their own research and discuss recent advances from the literature. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. May be repeated for credit. R. Mehta

281I. Topics in Disease Ecology, Population Biology, and Conservation. F,W,S
Selected topics in population biology and disease ecology. Students present results from their own research and discuss recent advances from the literature. (Formerly "Topics in Plant Population and Disease Ecology") Enrollment restricted to graduate students; qualified undergraduates may enroll by permission of instructor. Enrollment limited to 18. May be repeated for credit. A. Kilpatrick

281J. Topics in Research on Biochemical Ecology. *
Seminar in which students give critically evaluated presentations regarding current research on selected topics in plant ecology with an emphasis on biochemical ecology. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. Enrollment limited to 12. May be repeated for credit. J. Langenheim

281K. Topics in Plant Evolution. F,W,S
Intensive seminar on selected topics in plant evolution. Students present results from their own research and discuss recent advances from the literature. Enrollment restricted to graduate students; qualified undergraduates may enroll by permission of instructor. Enrollment limited to 18. May be repeated for credit. K. Kay

281L. Topics in Behavioral and Evolutionary Ecology. F,W,S
An intensive seminar on selected topics in behavioral and evolutionary ecology. Students are expected to discuss the current literature and present literature reviews, research proposals, and preliminary results from their ongoing research. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. Enrollment limited to 10. B. Lyon

281N. Topics in Marine Vertebrate Ecology. F,W,S
Seminar on the ecology of marine vertebrates. Topics vary from the factors that explain the distribution of marine predators to island biogeography and the ecosystem effects of introduced vertebrates on islands. Enrollment restricted to graduate students. Enrollment limited to 12. May be repeated for credit. D. Croll

281O. Topics in Plant-Water Relations. F,W,S
Intensive seminar focusing on fundamental and evolutionary concepts in plant-water relations. Students present results from their own research and discuss recent advances from the literature. Enrollment restricted to graduate students; qualified undergraduates may enroll by permission of instructor. Enrollment limited to 18. May be repeated for credit. J. Pittermann

281P. Topics in Plant Population Ecology. F,W,S
An intensive seminar on selected topics in plant ecology and population biology. Students present results from their own research and discuss recent advances from the literature. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission from instructor. Enrollment limited to 12. May be repeated for credit. I. Parker

281Q. Topics in Molecular Evolutionary Genetics. F,W,S
An intensive seminar on selected topics in molecular evolutionary genetics. Students are required to present results from their own research projects, present a critical review paper at least once during the quarter, and submit a written research proposal. Enrollment restricted to graduate students; qualified undergraduate students may enroll with permission of instructor. Enrollment limited to 10. May be repeated for credit. G. Pogson

281R. Topics in Marine Ecology and Evolutionary Biology. F,W,S
An intensive seminar series focusing on fundamental concepts in marine ecology. Emphasis changes quarter to quarter. At least one quarter per year is devoted to discussion of graduate student research. Other quarters involve reading and evaluating current and classic literature on marine ecology and evolutionary biology. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. Enrollment limited to 10. May be repeated for credit. P. Raimondi

281T. Species Interactions and Coevolution. F,W,S
The genetics and ecological structure of species interactions, and the role of coevolution between species in shaping biodiversity. Enrollment restricted to graduate students. Enrollment limited to 15. May be repeated for credit. J. Thompson

281U. Topics in Invertebrate Biology. F,W,S
An intensive study about concepts, theory, and techniques for graduate students conducting research on the ecology, genetics, evolution, systematics, or biodiversity of marine invertebrates. Enrollment restricted to graduate students; advanced undergraduates may enroll with permission of instructor. Enrollment limited to 15. May be repeated for credit. D. Potts

281V. Topics in Behavioral Ecology. F,W,S
A discussion of current topics and methods in behavioral ecology and life history evolution. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. May be repeated for credit. B. Sinervo

281W. Topics in Exercise and Environmental Physiology. F,W,S
A weekly seminar discussion on current research and techniques in mammalian exercise and environmental physiology. Areas covered include locomotor physiology, exercise testing and cardiovascular monitoring, and biomechanics. Oral presentation of ongoing research or current literature required from each student. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. May be repeated for credit. T. Williams

286. Experimental Design and Data Analysis. W
Focuses on problems and designs in ecology and population biology. Topics include basic experimental design; exploratory data analysis—from a graphical perspective; hands-on statistics; and graphical theory. Structured around a statistical analysis and graphics computer program to teach students to design their own surveys and experiments and analyze their data correctly. Students cannot receive credit for this course and course 186. Prerequisite(s): one course in statistics or by permission of instructor. Enrollment restricted to graduate students. P. Raimondi

286L. Experimental Design and Data Analysis Lab (2 credits). W
Required lab that accompanies Biology 286. Lab will focus on hands-on statistical problem solving, graphical presentations and experimental design issues. Concurrent enrollment in course 286 is required. Enrollment restricted to graduate students. P. Raimondi

293. Readings in Ecology and Evolution (2 credits). W,S
Weekly readings and discussions of recent research papers in ecology, evolution, and related topics from organismal biology. Enrollment restricted to graduate students. May be repeated for credit. The Staff

294. Ecology, Evolutionary Biology Seminar (no credit). F,W,S
Selected topics of current interest to ecologists and evolutionary biologists presented by weekly guest speakers. Enrollment restricted to graduate students. The Staff

295. Advanced Ecology and Evolutionary Biology Seminar (no credit). F,W,S
Course consists of extended weekly meetings organized around an advanced theme in theoretical or applied evolutionary biology, ecology, physiology, behavior, or other aspect of oranismal biology. Course is targeted at students who already have reached a professional level of expertise in their field and advanced master students. Enrollment restricted to graduate students. Enrollment limited to 24. The Staff

297. Independent Study. F,W,S
Independent study for graduate students who have not yet settled on a research area for their thesis. Students submit petition to sponsoring agency. The Staff

299. Thesis Research. F,W,S
Students submit petition to sponsoring agency. The Staff  

Biology: Molecular, Cell, and Developmental

Lower-Division Courses

15. Undergraduate Research Reports (1 credit). F,W,S
Undergraduate students who work in faculty research laboratories present the results of their projects. Organized by the Minority Undergraduate Research Program and the Minority Access to Research Careers Program. Designed for students with membership in the above-mentioned programs. Prerequisite(s): qualifications as determined by instructor at first class meeting. May be repeated for credit. B. Bowman

20A. Cell and Molecular Biology. F,W,S
Introduction to molecular biology, cell physiology, and genetics. Prerequisite(s): Chemistry 1A and 1B. (General Education Code(s): IN.) M. Ares, M. Dalbey, B. Bowman

20L. Experimental Biology Laboratory (2 credits). F,W,S
Provides biology majors with the theory and practice of experimental biology. A wide range of concepts and techniques used in the modern laboratory are included in the exercises. Designed to satisfy the introductory biology lab requirement of many medical and professional schools. Students are billed a materials fee. Prerequisite(s): BIOL 20A and previous or concurrent enrollment in BIOE 20B. Enrollment restricted to human biology and health sciences majors; other majors by permission. Enrollment limited to 20. M. Dalbey, L. Ogren

80A. Female Physiology and Gynecology. S
Biochemical, medical, social, and clinical aspects of the female body. Emphasis will be on biological-chemical interactions in the female organs. Topics include female anatomy, cell physiology, endocrine functions, sexuality and intimacy, sexually transmitted diseases, puberty, pregnancy, menopause, birth control, abortion, immunity, cancer. (General Education Code(s): SI, T-2 Natural Sciences.) M. Zavanelli

80E. Evolution. *
Introduction to Darwinian evolution including how the theory was devised and a discussion of other theories proposed at the time. Explores the facts and evidence of evolutionary processes and the insights they provide in biological diversity, consequences of extinction, and emergence of new diseases. Includes a discussion of evolution and spirituality. (General Education Code(s): SI, T-2 Natural Sciences.) M. Zavanelli

80J. Biology of AIDS. W
An overview of the biology of the acquired immunodeficiency syndrome (AIDS) and the social and legal issues that surround it are explored in a series of lectures by biology faculty and experts in the field. (General Education Code(s): SI, T-2 Natural Sciences.) M. Zavanelli

Upper-Division Courses

100. Biochemistry. F,S
An introduction to biochemistry including biochemical molecules, protein structure and function, membranes, bioenergetics, and regulation of biosynthesis. Provides students with basic essentials of modern biochemistry and the background needed for upper-division biology courses. Students who plan to do advanced work in biochemistry and molecular biology should take the Biochemistry and Molecular Biology 100 series directly. Students cannot receive credit for this course after they have completed any two courses from the BIOC 100A, 100B, and 100C sequence with grades of Pass, C, or better. Prerequisite(s): BIOL 20A and BIOE 20B; and CHEM 108A or 112A. Concurrent enrollment in course 100K is required. J. Sanford, M. Dalbey

100K. Biochemistry Laboratory (2 credits). F,W,S
Laboratory course providing hands-on experience with, and covering conceptual background in, fundamental techniques in molecular biology and biochemistry, including DNA cloning, PCR, restriction digest, gel electrophoresis, protein isolation, protein quantification, protein immunoblot (Western) analysis, and use of online bioinformatics tools. Students are billed a materials fee. Concurrent enrollment in course 100 or BIOC 100A is required. J. Lee

100L. Advanced Biochemistry Laboratory. W
Basic techniques and principles of laboratory biochemistry including isolation and characterization of a natural product, manipulation of proteins and nucleic acids to demonstrate basic physical and chemical properties; and characterization of enzyme substrate interactions. Students are billed a materials fee. (Formerly Biochemistry Laboratory). Prerequisite(s): previous or concurrent enrollment in BIOL 100; satisfaction of the Entry Level Writing and Composition requirements. Enrollment restricted to biological sciences and affiliated majors; biology minors; non-majors by instructor permission. Enrollment limited to 20. (General Education Code(s): W.) M. Dalbey

105. Genetics. F,W,S
Mendelian and molecular genetics; mechanisms of heredity, mutation, recombination, and gene action. Prerequisite(s): BIOL 20A. M. Dalbey, N. Bhalla, R. Kamakaka

105L. Eukaryotic Genetics Laboratory. F,W
Classical and newly developed molecular-genetic techniques used to explore genetic variation in wild populations of the fruit fly Drosophila melanogaster. Topics include Mendelian fundamentals, mapping, design of genetic screens, bio-informatic and database analysis, genetic enhancers, and population genetics. Students are billed a materials fee. Prerequisite(s): BIOL 105; BIOL 100 or BIOC 100A recommended; satisfaction of Entry Level Writing and Composition Requirements. Enrollment restricted to biological sciences and affiliated majors; biology minors; non-majors by instructor permission. (General Education Code(s): W.) J. Lee

105M. Microbial Genetics Laboratory. *
Exploration of basic genetics processes such as replication, mutation, DNA repair, recombination, gene exchange, population genetics, and evolution using microbial model organisms; classic techniques in microbial genetics and contemporary molecular techniques presented. Students are billed a materials fee. Prerequisite: BIOL 105; satisfaction of the Entry Level Writing and Composition requirements. Enrollment restricted to biological sciences and affiliated majors; biology minors; other majors by instructor permission. Enrollment limited to 16. (General Education Code(s): W.) M. Dalbey

109L. Yeast Molecular Genetics Laboratory. *
The powerful genetic and molecular techniques available for yeast combined with the complete genomic DNA sequence offers opportunity for discovery of fundamental aspects of eukaryotic life. Lab providing practical experience in using yeast as an experimental system. Students are billed a materials fee. Prerequisite(s): BIOL 105; BIOL 115 strongly recommended; satisfaction of the Entry Level Writing and Composition requirements. Enrollment restricted to biological sciences and affiliated majors; biology minors; other majors by instructor permission. Enrollment limited to 15. (General Education Code(s): W.) The Staff

110. Cell Biology. F,S
Covers the structure, organization, and function of eukaryotic cells. Topics include biological membranes, organelles, protein and vesicular trafficking, cellular interactions, the cytoskeleton, and signal transduction. Requires a good understanding of basic biochemistry and molecular biology. Prerequisite(s): BIOL 105, and BIOL 100 or BIOC 100A. D. Feldheim, L. Hinck

110L. Cell Biology Laboratory. S
Fundamental aspects of cell biology explored through experimentation in a modern laboratory setting. Research topics include the structure and function of biological membranes; intracellular transport and organelle biogenesis; the cell cycle; and the cytoskeleton. Students are billed a materials fee. Prerequisite(s): BIOL 100 or BIOC 100A; previous/concurrent enrollment in course 110; satisfaction of the Entry Level Writing and Composition requirements. Restricted to biological sciences/affilitated majors; biology minors; other majors by permission. Enrollment limited to 16. (General Education Code(s): W.) M. Rexach

111A. Immunology I. W
Principles and concepts of the innate and adaptive immune systems, with emphasis on mechanisms of action and molecular and cellular networks. The development, differentiation, and maturation of cells of the immune system are also discussed. Prerequisite(s): courses BIOE 20B, and BIOL 20A, 105, and 110. M. Zuniga

111B. Immunology II. S
The immune system in health and disease, including failures of host immune-defense mechanisms, allergy and hypersensitivity, autoimmunity, transplantation biology, the immune response to tumors, immune-system interactions with pathogens, and manipulation of the immune response. Prerequisite(s): courses BIOE 20B, and 20A, 105, 110, and 111A. M. Zuniga

113. Mammalian Endocrinology. S
Introduction to the major endocrine organs, their hormones, and their receptors. Emphasis is on the following topics: structural analysis of the hormones and receptors at the protein and molecular level, regulation of expression of hormones and their receptors, and the biological functions of hormones. Prerequisite(s): BIOL 100 or BIOC 100A. L. Ogren

114. Cancer Cell Biology. *
Focuses on the molecular and cellular mechanisms behind cancer. Topics covered include oncogenes, tumor suppressor genes, cell growth genes, checkpoint genes, telomeres, and apoptosis. Students will gain experience in reading the primary scientific literature. Prerequisite(s): BIOL 110 or 115. (General Education Code(s): TA.) A. Zahler

115. Eukaryotic Molecular Biology. W,S
Covers eukaryotic gene and genome organization; DNA, RNA, and protein synthesis; regulation of gene expression; chromosome structure and organization; and the application of recombinant DNA technology to the study of these topics. Prerequisite(s): BIOL 100 or BIOC 100A, and BIOL 105. Enrollment restricted to biological sciences and affiliated majors, non-majors by permission of instructor. H. Boeger, M. Jurica

115L. Eukaryotic Molecular Biology Laboratory. F,W,S
A laboratory designed to provide students with direct training in basic molecular techniques. Each laboratory is a separate module which together builds to allow cloning, isolation, and identification of a nucleic acid sequence from scratch. Students cannot receive credit for this course and course 187L or 287L. Students are billed a materials fee. Prerequisite(s): BIOL 100 or BIOC 100A; previous/concurrent enrollment in course 115; satisfaction of the Entry Level Writing and Composition requirements. Restricted to biological sciences/affiliated majors; biology minors; other majors by permission. Enrollment limited to 20. (General Education Code(s): W.) M. Zavanelli

118. Pathogenesis: Molecular Mechanisms of Disease. *
Overview of the pathogenic mechanisms underlying human disease at the physiological and molecular levels, with their implications for epidemiology, diagnosis, and treatment. Includes discussion of clinical cases and of emerging areas of research. Geared toward students interested in future research or clinical careers in the area of human or animal health. Students cannot receive credit for this course and Microbiology and Environmental Toxicology 238. (Also offered as Microbiol & Environ Toxicology 138. Students cannot receive credit for both courses.) Prerequisite(s): Biology 130. Enrollment restricted to students majoring in biology; human biology; molecular, cell and developmental biology; biochemistry and molecular biology; or neuroscience. Offered in alternate academic years. M. Camps

119. Microbiology. F,W
Cell and molecular biology of bacteria and their viruses, including applications in medicine, public health, agriculture, and biotechnology. (Also offered as Microbiol & Environ Toxicology 119. Students cannot receive credit for both courses.) Prerequisite(s): BIOL 100 or BIOC 100A. V. Stone, F. Yildiz

119L. Microbiology Laboratory. F,W,S
An introduction to the principles and practices of laboratory microbiology, with a substantial presentation of optical microscopy. Students are billed a materials fee. (Also offered as Microbiol & Environ Toxicology 119L. Students cannot receive credit for both courses.) Prerequisite(s): previous or concurrent enrollment in BIOL 119 is required; satisfaction of Entry Level Writing and Composition requirements. Enrollment restricted to biological sciences and affiliated majors; biology minors; other majors by permission. (General Education Code(s): W.) C. Saltikov, K. Ottemann

120. Development. W
A description and analysis of selected developmental events in the life cycle of animals. Experimental approaches to understanding mechanisms are emphasized. Prerequisite(s): BIOL 100 or BIOC 100A, and BIOL 105 and BIOL 110. J. Lee

120L. Development Laboratory. *
Experimental studies of animal development using a variety of locally obtainable organisms. Approximately eight hours weekly, but it will often be necessary to monitor continuing experiments throughout the week. Students are billed a materials fee. Prerequisite(s): satisfaction of the Entry Level Writing and Composition requirements; previous or concurrent enrollment in BIOL 120 required. Enrollment restricted to biological sciences and affiliated majors; biology minors; other majors by permission. J. Lee

121L. Environmental Phage Biology Laboratory. F
Introduction to hypothesis-driven laboratory research. Students isolate a unique bacteriophage and characterize its structure and genome. An understanding of molecular biology and basic genetics required. Students are billed a materials fee. Enrollment by online application and permission of instructor. Enrollment restricted to biological sciences and affiliated majors with sophomore standing or higher. Prerequisite(s): satisfaction of the Entry Level Writing and Composition requirements. Enrollment limited to 20. G. Hartzog

125. Introduction to Neuroscience. F
The structure and function of the nervous system. Topics include elementary electrical principles, biophysics and physiology of single nerve and muscle cells, signal transduction at synapses, development of the nervous system, and neural basis of behavior. Requires a good understanding of basic biochemistry, cell biology, and molecular biology. Prerequisite(s): BIOL 100. Concurrent enrollment in BIOL 105 or 110 is encouraged. B. Chen

126. Advanced Molecular Neuroscience. W
Explores in detail cellular and molecular events that underlay the function of the nervous system. Topics include neural development, axon guidance and regeneration, advanced electrical principles (synaptic transmission through a variety of receptors), synaptic plasticity, learning and memory, as well as several neural disorders. Prerequisite(s): BIOL 125. (General Education Code(s): TA.) Y. Zuo

127. Mechanisms of Neurodegenerative Disease. S
Focuses on cellular and molecular processes that underlie neurodegenerative diseases. Includes lectures, student oral presentations, discussions, a term paper, and exams. Prerequisite(s): BIOL 105 and 110. (General Education Code(s): TA.) W. Saxton

130. Human Physiology. F,W
Function, organization, and regulation of the major organ systems of humans, with emphasis on integration among systems. Students cannot receive credit for this course and course 131. Prerequisite(s): BIOL 20A, BIOE 20B, BIOL 100 or BIOC 100A, and BIOL 110. L. Ogren

130L. Human Physiology Laboratory (2 credits). F,W
Examines fundamental principles of systemic physiology focusing on the human. Students cannot receive credit for this course and BIOE 131L. Students are billed a materials fee. Prerequisite(s): satisfaction of the Entry Level Writing and Composition requirements; BIOL 20A, BIOE 20B, BIOL100, and BIOL 110. Previous or concurrent enrollment in BIOL130 is required; restricted to biological sciences and affiliated majors; biology minors; other majors by permission. L. Ogren

140. Biophysics. S
Physical principles and techniques used in biology: X-ray diffraction; nuclear magnetic resonance; statistics, kinetics, and thermodynamics of macromolecules; viscosity and diffusion; DNA/RNA pairing; electrophoresis; physics of enzymes; biological energy conversion; optical tweezers. (Also offered as Physics 180. Students cannot receive credit for both courses.) Enrollment restricted to juniors and seniors. J. Deutsch

178. Stem Cell Biology. W
Basic concepts, experimental approaches, and therapeutic potential are discussed. Students gain experience in reading the primary scientific literature. (Also offered as Biomolecular Engineering 178. Students cannot receive credit for both courses.) Prerequisite(s): BIOL 110; BIOL 115 recommended. C. Forsberg

178L. Protocols in Stem Cell Biology. W
Provides hands-on experience in embryonic stem cell culture methods and techniques. Students grow and passage mouse embryonic stem (mES) cells and perform established protocols that differentiate mES cells into cardiac muscle cells and neurons. Prerequisite(s): satisfaction of the Entry Level Writing and Composition requirements; previous or concurrent enrollment in course 178. Enrollment restricted to biological sciences and affiliated majors; biology minors; non-majors by permission. Enrollment limited to 16. D. Feldheim

179. Biotechnology and Drug Development. W
Recommended for students interested in careers in the biopharmaceutical industry. Focuses on recombinant DNA technology and the drug-development process, including discovery research; preclinical testing; clinical trials; and regulatory review, as well as manufacturing and production considerations. Students may not receive credit for this course and Biomolecular Engineering 255 and Chemistry 255. (Also offered as Biomolecular Engineering 155. Students cannot receive credit for both courses.) Prerequisite(s): BIOL 20A and BIOL 100 or BIOC 100A. Enrollment limited to 15. P. Berman

180. Research Programming for Biologists and Biochemists. S
No programming experience required, but basic computer skills assumed. Students without prior programming experience taught basic proficiency in Perl, BioPerl, and other Perl libraries needed to analyze, transform, and publish biological data. Students required to solve a research problem as a final project. Lectures and labs are shared with Biomolecular Engineering 60. Students cannot receive credit for this course and Biomolecular Engineering 60. (Also offered as Biomolecular Engineering 160. Students cannot receive credit for both courses.) Prerequisite(s): BIOL 20A or BIOL 21A. Concurrent enrollment in BIOL 180L is required. (General Education Code(s): MF.) The Staff

180L. Research Programming for Biologists and Biochemists Laboratory (1 credit). S
Laboratory sequence illustrating topics covered in course 160. One two-hour laboratory per week. Students cannot receive credit for this course and Biomolecular Engineering 60L. (Also offered as Biomolecular Engineering 160L. Students cannot receive credit for both courses.) Prerequisite(s): BIOL 20A or BIOL 21A. Concurrent enrollment in BIOL 180 is required. The Staff

181. Computational Biology Tools. F,S
Hands-on laboratory geared to teach basic tools used in computational biology (motif searching, primer selection, sequence comparison, multiple sequence alignment, genefinders, phylogenetics analysis, X-ray crystallography software). Web- and Unix-based tools/databases are used. Open to all science students; no prior Unix experience required. (Also offered as Biomolecular Engineering 110. Students cannot receive credit for both courses.) Prerequisite(s): course 100, 105, or Biochemistry 100A or declared bioinformatics majors. Enrollment limited to 25. D. Gerloff, T. Lowe

182. Genomes. F
Advanced elective for biology majors, examining biology on the genome scale. Topics include genome sequencing; large scale computational and functional analysis; features specific to prokaryotic, eukaryotic, or mammalian genomes; proteomics; SNP analysis; medical genomics; and genome evolution. (Also offered as Biomolecular Engineering 130. Students cannot receive credit for both courses.) Prerequisite(s): Biology 100 or Biochemistry 100A and Biology 105, or approval of instructor. Enrollment limited to 30. The Staff

186F. Undergraduate Research in MCD Biology (2 credits). F,W,S
Supervised undergraduate research in laboratory of an MCD biology faculty member accompanied by weekly lectures on ethical and practical scientific issues. Topics include laboratory safety; the scientific method; the collection, treatment, and presentation of data; critical evaluation of scientific literature; scientific misconduct; and peer review. Career issues, including how to apply for admission to graduate and professional schools, also discussed. Prerequisite(s): BIOL 20A and BIOE 20B; at least one of BIOL 100, BIOL 105, or BIOC 100A; and permission of instructor. May be repeated for credit. The Staff

186L. Undergraduate Research in MCD Biology. F,W,S
Supervised undergraduate research in laboratory of an MCD biology faculty member accompanied by weekly lectures on ethical and practical scientific issues. Topics include laboratory safety; the scientific method; the collection, treatment, and presentation of data; critical evaluation of scientific literature; scientific misconduct; and peer review. Career issues, including how to apply for admission to graduate and professional schools, also discussed. Prerequisite(s): satisfaction of the Entry-Level Writing and Composition requirements; courses BIOL 20A and BIOE 20B; at least one of BIOL 100, BIOL 105, or BIOC 100A; and permission of instructor. (General Education Code(s): W.) The Staff

186R. Undergraduate Research in MCD Biology. F,W,S
Supervised undergraduate research in the laboratory of an MCD biology faculty member accompanied by weekly lectures on practical scientific issues. Topics include: laboratory safety; the scientific method; the collection, treatment, and presentation of data; critical evaluation of scientific literature; ethics and scientific misconduct; and peer review. Career issues, including how to apply for admission to graduate and professional schools, are discussed. Students cannot receive credit for this course and course 186L. Prerequisite(s): BIOL 100K and previous completion of the Disciplinary Communication requirement, and permission of instructor. May be repeated for credit. The Staff

187L. Molecular Biotechnology Laboratory. F
An intensive molecular biology laboratory that presents procedures used in molecular and biotechnology research. Topics and procedures include DNA/RNA isolation, cloning and library construction, southern and northern hybridization, DNA fingerprinting, PCR, manual and automated sequencing, and computer methods for analyzing molecular data. New procedures currently being developed in biotechnology industries are presented by industry representatives. Students cannot receive credit for this course and BIOL 116L or BIOL 287L. Students are billed a materials fee. Prerequisite(s): satisfaction of the Entry Level Writing and Composition requirements and BIOL 20A, BIOE 20B, BIOE 20C, BIOL 100, and BIOL 110. Enrollment limited to 20. M. Zavanelli

189. Health Sciences Internship (3 credits). F,W,S
Structured off-campus learning experience providing hands-on experience and pre-professional mentoring in a variety of health-related settings. Interns are trained and supervised by a professional at their placement and receive academic guidance from their faculty sponsor. Students spend 10-12 hours per week at their placement, participate in weekly discussion meetings on campus, keep a reflective journal, and submit a final paper. Enrollment by application. Students interview with health sciences internship coordinator; applications are due one quarter in advance to the Health Sciences Internship Office. Prerequisite(s): satisfaction of the Entry Level Writing and Composition requirements; concurrent enrollment in course 189W is required. Enrollment restricted to human biology majors. The Staff

189F. Health Sciences Internship (2 credits). F,W,S
Structured off-campus learning experience providing hands-on experience and pre-professional mentoring in a variety of health-related settings. Interns are trained and supervised by a professional at their placement, and receive academic guidance from their faculty sponsor. Students spend six hours per week at their placement, keep a reflective journal, and submit a final paper. Enrollment by application. Students interview with health sciences internship coordinator. Applications due one quarter in advance to the Health Sciences Internship Office. May be repeated for credit. The Staff

189W. Disciplinary Communication: Human Biology (2 credits). F,W,S
Writing-intensive course offered in conjunction with the health sciences internship. Weekly class meetings include academic guidance and mentoring as well as discussion of the mechanisms and conventions of academic writing about heath and health care. Students complete multiple writing assignments, culminating in a term paper in the format of a scholarly article. Enrollment by application. Students interview with the health-sciences internship coordinator; applications are due one quarter in advance to the Health Care Sciences Internship Office. Prerequisite(s): satisfaction of the Entry Level Writing and Composition requirements. Previous or concurrent enrollment in course 189 is required. Enrollment restricted to human biology majors. G. Hartzog

190. Senior Seminar (2 credits). S
Satisfies the senior exit requirement for all biological sciences majors. (Also offered as Biology:Ecology & Evolutionary 190. Students cannot receive credit for both courses.) The Staff

191. ACE Program Service Learning (2 credits). F
Students participate in training and development to co-facilitate collaborative learning in ACE chemistry discussion sections and midterm/exam review sessions. Students are role models for students pursuing science- and math-intensive majors. Prerequisite(s): Prior participation in ACE; good academic standing; no non-passing grades in prior quarter. Enrollment restricted to sophomores, juniors, and seniors. (Formerly course 182.) Enrollment limited to 10. (General Education Code(s): PR-S.) The Staff

195. Senior Thesis Research. F,W,S
An individually supervised course, with emphasis on independent research, to culminate in a senior thesis. Students submit petition to sponsoring agency. May be repeated for credit. The Staff

198. Independent Field Study. F,W,S
Provides for individual programs of study (a) by means other than the usual supervision in person, or (b) when the student is doing all or most of the course work off campus. With permission of the department, may be repeated for credit, or two or three courses taken concurrently. Students submit petition to sponsoring agency. May be repeated for credit. The Staff

198F. Independent Field Study (2 credits). F,W,S
Provides for two units of independent field study (a) by means other than the usual supervision in person, or (b) when the student is doing all or most of the course work off campus. Students submit petition to sponsoring agency. May be repeated for credit. The Staff

199. Tutorial. F,W,S
Reading, discussion, written reports, and laboratory research on selected biological topics, using facilities normally available on campus. Students submit petition to sponsoring agency. May be repeated for credit. The Staff

199F. Tutorial (2 credits). F,W,S
Two-unit Tutorial. Reading, discussion, written reports, and laboratory research on selected biological topics, using facilities normally available on campus. Students submit petition to sponsoring agency. May be repeated for credit. The Staff

Graduate Courses

200A. Critical Analysis of Scientific Literature. F
Development of critical thinking skills via discussion of research articles on a broad range of topics. Prepares students to critically evaluate research publications, and improves their ability to organize effective oral presentations and to evaluate the oral presentations of other scientists. Enrollment restricted to graduate students in MCD biology, or by permission of instructor. Enrollment limited to 20. W. Saxton

200B. Advanced Molecular Biology. F
An in-depth coverage of the structure, function, and synthesis of DNA, RNA, and proteins. Discussion of the roles of macromolecules in the regulation of information in the cell. Prerequisite(s): Enrollment restricted to graduate students. R. Kamakaka, M. Ares

200C. Advanced Cell Biology. W
An in-depth coverage of topics in cellular and subcellular organization, structure, and function in plants and animals. Emphasis on current research problems. Prerequisite(s): BIOL 200B. Enrollment restricted to graduate students. W. Sullivan

200D. Developmental Biology. S
Key topics in developmental biology, including developmental genetics, epigenetics, stem cell biology, and developmental neurobiology. Lectures are accompanied by critical analysis and discussion of recent publications. Enrollment restricted to graduate students in MCD biology, or by permission of instructor. Enrollment limited to 20. S. Strome

201. RNA Processing. *
An advanced graduate-level course on biological aspects of RNA function and processing in eukaryotes. Lectures and discussions will be developed using the current literature. Prerequisite(s): BIOL 200B or permission of instructor. Enrollment restricted to graduate students. Enrollment limited to 15. M. Ares

203. Ribosomes and Translation. *
Covers the field of ribosome research in depth, including the structure and function of ribosomes and the molecular mechanisms of protein synthesis. Begins with historical review of the ribosome field and proceeds to the most recent findings. Focus is on central questions: (1) How is the accuracy of the aminoacyl-tRNA selection determined? (2) What is "accommodation"? (3) What is the mechanism of peptide bond formation (peptidyl transferase)? (4) What is the mechanism of translocation? (5) What are the mechanistic roles of the ribosome and translation factor EF-G in translocation? (6) To what extent is the mechanism of translation determined by RNA? (7) Why is RNA so well suited for the ribosome? (8) How did translation evolve from an RNA world? Prerequisite(s): BIOC 100A,BIOL 200B or permission of instructor. Enrollment restricted to graduate students. H. Noller

204. Chromatin. *
Eukaryotic DNA is complexed with histones to form chromatin. This course focuses on the ways in which chromatin influences and is manipulated to regulate gene expression. Prerequisite(s): BIOL 105 and BIOL 115; undergrads by permission of instructor. Enrollment restricted to graduate students. Enrollment limited to 15. Offered in alternate academic years. J. Tamkun, G. Hartzog

205. Epigenetics. *
In-depth coverage of epigenetics focusing on how alterations in chromatin structure and DNA methylation establish and maintain heritable states of gene expression. Lectures are supplemented with critical discussion of recent publications. Prerequisite(s): BIOL 105 and BIOL 115, or permission of instructor. Enrollment restricted to graduate students. Enrollment limited to 20. S. Strome, J. Tamkun

206. Introduction to Stem Cell Biology. F
Fundamental concepts, experimental approaches, and current advances in stem cell biology, with consideration of key ethical issues. Topics include: self-renewal and differentiation; the microenvironment; epigenetics; cell-cycle regulation; and how basic research translates to medical therapeutics. Ethical, moral, and political issues surrounding stem cell research are discussed with lectures from philosophy and other relevant disciplines. Enrollment restricted to graduate students. Enrollment limited to 15. W. Sullivan

206L. Current Protocols in Stem Cell Biology. W
Provides students with hands-on experience in embryonic stem cell culture methods. Enrollment restricted to graduate students; qualified undergraduates may enroll by permission of instructor. Enrollment limited to 10. D. Feldheim

208. Cellular Signaling Mechanisms. *
All eukaryotic cells utilize intricate signaling pathways to control such diverse events as cell-cell communication, cell division, and changes in cell morphology. This course covers the molecular basis of these cellular signaling pathways, focusing on the most current research. Prerequisite(s): BIOL 105, BIOL 110, and BIOL 115. Enrollment restricted to seniors and graduate students. Enrollment limited to 15. Offered in alternate academic years. D. Kellogg

214. Cancer Cell Biology. *
Focuses on molecular and cellular mechanisms behind cancer. Topics include oncogenes, tumor suppressor genes, cell growth genes, checkpoint genes, telomeres, and apoptosis. Students gain experience in understanding the cutting edge of cancer drug design and formulate their own proposals for applying molecular and cellular biological techniques toward cancer diagnosis and treatment. Enrollment restricted to graduate students. Enrollment limited to 10. A. Zahler

226. Advanced Molecular Neuroscience. W
Basis of neural behavior at the cellular, molecular and system levels. First half of course focuses on cellular, molecular, and developmental aspects of the nervous system and covers two sensory systems: olfaction and auditory. Last half of course concerns higher-level functions of the nervous system, such as processing and integrating information. Discusses human diseases and disorders. Enrollment restricted to graduate students. Y. Zuo

280A. Topics in Research on Molecular Genetics of Yeast (2 credits). F,W,S
Intensive research seminar on the structure and function of the gene expression machinery in the simple eukaryote Saccharomyces cervisiae and its relationship to the human gene expression machinery. Enrollment restricted to graduate students; qualified undergraduates may enroll with approval of instructor. May be repeated for credit. M. Ares

280B. Chromatin Structure and Transcriptional Regulation (2 credits). F,W,S
Weekly seminar on structure and gene regulatory function of chromatin. Discusses research of participants and relevant scientific literature. Enrollment restrIcted to graduate students; qualified undergraduates may enroll with permission of instructor. Enrollment limited to 10. May be repeated for credit. H. Boeger

280C. Mammalian Brain Development (2 credits). F,W,S
Seminar covers research into the development of the mammalian brain. Enrollment restricted to graduate students; undergraduates may enroll with permission of instructor. Enrollment limited to 10. May be repeated for credit. B. Chen

280D. RNA Processing (2 credits). F,W,S
A discussion of current research and literature concerning the regulation of precursor messenger RNA processing. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. Enrollment limited to 10. May be repeated for credit. A. Zahler

280E. Meiotic Chromosome Dynamics (2 credits). F,W,S
Intensive course on the molecular mechanisms underlying homolog pairing, synapses, and recombination; and how they are regulated, coordinated, and monitored to ensure accurate meiotic chromosome segregation. Enrollment restricted to graduate students; undergraduates may enroll with permission of instructor. May be repeated for credit. N. Bhalla

280F. Development of Vertebrate Neural Connections (2 credits). F,W,S
Intensive research seminar on molecular mechanisms by which neural connections are established during mouse development. Special focus on topographic maps and role of Eph receptors and ephrins in this process. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. May be repeated for credit. D. Feldheim

280H. Topics on Research into Chromatin and Transcription (2 credits). F,W,S
Seminar covering research into the effects of chromatin on transcription in yeast. Enrollment restricted to graduate students; undergraduates may enroll with permission of instructor. Enrollment limited to 10. May be repeated for credit. G. Hartzog

280I. Epigenetic Gene Silencing and Insulators (2 credits). F,W,S
Intensive course on molecular mechanisms by which insulator elements regulate epigenetic gene silencing. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. May be repeated for credit. R. Kamakaka

280J. Structures of Macromolecular Complexes (2 credits). F,W,S
Focuses on structure and function of the spliceosome using electron microscopy and x-ray crystallography. Participants present results from their own research and relevant journal articles. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. Enrollment limited to 20. May be repeated for credit. M. Jurica

280K. Topics in Cell Cycle Research (2 credits). F,W,S
An intensive seminar focusing on current research on the molecular mechanisms that control cell division. Participants are required to present results of their own research or to review journal articles of interest. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. D. Kellogg

280L. Topics on Neural Development (2 credits). F,W,S
Seminar covering research into breast development and cancer. Enrollment restricted to graduate students. Enrollment limited to 12. May be repeated for credit. L. Hinck

280M. Post-Transcriptional Control of Mammalian Gene Expression (2 credits). F,W,S
Intensive course on the molecular mechanisms by which RNA binding proteins regulate gene expression. Enrollment restricted to graduate students; qualified undergraduates may enroll with the permission of the instructor. Enrollment limited to 8. May be repeated for credit. J. Sanford

280N. Structure and Function of Ribosomes (2 credits). F,W,S
An intensive and advanced course focusing on the structure and function of ribosomes. Participants present research findings in an organized, critical fashion, in the context of current research literature in the ribosome field. Enrollment restricted to graduate students; qualified undergraduate students may enroll with permission of the instructor. Enrollment limited to 20. May be repeated for credit. H. Noller

280O. Topics in Bacterial Pathogenesis (2 credits). F,W,S
Intensive seminar focusing on mechanisms of bacterial pathogenesis of the ulcer-causing bacterium Helicobacter pylori. Participants are required to present results from their own research and relevant journal articles. (Also offered as Microbiol & Environ Toxicology 281O. Students cannot receive credit for both courses.) Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. Enrollment limited to 20. May be repeated for credit. K. Ottemann

280Q. Cell Biology of Oocytes, Embryos, and Neurons (2 credits). F,W,S
Weekly seminar and round-table discussion about research problems and recent advances in molecular motor proteins, cytoskeletons, and the control of force-producing processes. Each participant reports recent advances in their field from current literature, their own primary research questions, current approaches to answering those questions, and their research progress. Enrollment restricted to graduate students; undergraduates may enroll with permission of instructor. Enrollment limited to 10. May be repeated for credit. W. Saxton

280R. Structure and Function of the Nuclear Pore Complex (2 credits). F,W,S
Intensive and advanced course focusing on structure and function of the nuclear pore complex. Participants present research findings in an organized critical fashion in the context of current research literature in the nucleo-cytoplasmic transport field. Enrollment restrIcted to graduate students; qualified undergraduates may enroll with permission of instructor. Enrollment limited to 10. May be repeated for credit. M. Rexach

280S. Chromatin and RNA Regulation in C. elegans (2 credits). F,W,S
Intensive research seminar about regulators of chromatin organization; the composition and function of germ granules; and the roles of both levels of regulation in germline development in C. elegans. Participants present their research results and report on related journal articles. Enrollment restricted to graduate students; undergraduates may enroll with permission of instructor. Enrollment limited to 10. May be repeated for credit. S. Strome

280T. Molecular Biology of Drosophila Development (2 credits). F,W,S
An intensive seminar concerning the molecular genetics of Drosophila. Recent research is discussed weekly, with an emphasis on gene regulation and development. Students present their own research or critical reviews of recent articles at least once during the quarter. Enrollment restricted to graduate students. Qualified undergraduates may enroll with permission of instructor. Enrollment limited to 10. May be repeated for credit. J. Tamkun

280U. Discussions on the Development of the Drosophila Embryo (2 credits). F,W,S
Involves a two-hour weekly meeting in which the students discuss topics concerning the cell cycle, early embryonic development, and the cytoskeleton. These discussions critically evaluate ongoing research in this area. Material is drawn from student research and recently published journal articles. Students are also expected to meet individually with the instructor two hours weekly. In addition to a three–five page research proposal, each student gives two one-hour oral presentations. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. May be repeated for credit. W. Sullivan

280W. Membrane Proteins (2 credits). F
Seminar on recent research on membrane proteins, with an emphasis on ion-pumping ATPase. Enrollment restricted to graduate students; qualified undergraduates may enroll with permission of instructor. Enrollment limited to 20. May be repeated for credit. B. Bowman

280X. Mammalian Developmental and Stem Cell Biology (2 credits). F,W,S
Explores topics in developmental and stem cell biology, with emphasis on mammalian systems. Students present results of independent research projects in the context of relevant publications and other background information. Course meets once each week. Enrollment restricted to graduate students. May be repeated for credit. A. Ralston

280Y. Activity-Dependent Synaptic Plasticity (2 credits). F,W,S
Research seminar covering the regulation of synaptic plasticity in the mammalian nervous system, focusing on how the activity regulates the structural and functional dynamics of synapses. Enrollment restricted to graduate students; undergraduates may enroll with permission of instructor. Enrollment limited to 10. May be repeated for credit. Y. Zuo

289. Practice of Science. W
Examination of ethical and practical scientific issues, including the collection and treatment of data, attribution of credit, plagiarism, fraud, and peer review. Career issues, including how to apply for grants and positions in industry or academia, will be discussed. Prerequisite(s): BIOL 200A, BIOL 200B, and BIOL 200C or permission of instructor. Enrollment restricted to graduate students; undergraduates may enroll with permission of the instructor. Enrollment limited to 20. The Staff

291. Molecular, Cellular, and Developmental Biology Seminar (2 credits). F,W,S
Topics of current interest in molecular, cellular, and developmental biology are presented weekly by graduate students, faculty, and guest speakers. Enrollment restricted to graduate students. Enrollment limited to 60. May be repeated for credit. Y. Zuo

292. MCD Seminar (no credit). F,W,S
Various topics by weekly guest speakers. Enrollment restricted to graduate students. Y. Zuo

296. Laboratory Research in Molecular, Cell, and Developmental Biology. F,W,S
Independent laboratory research in molecular, cellular, and developmental biology. Students submit petition to sponsoring agency. May be repeated for credit. The Staff

297. Independent Study. F,W,S
Independent study for graduate students who have not yet settled on a research area for their thesis. Students submit petition to sponsoring agency. The Staff

299. Thesis Research. F,W,S
Students submit petition to sponsoring agency. The Staff  

*Not offered in 2011-12

Revised: 8/13/12